Clinical Trials

Actively registered and completed trials on Grid Therapy, Lattice Therapy, and SFRT, pulled directly from ClinicalTrials.gov.

Trials

Showing 20 of 43 trials
  1. Lattice Radiation Therapy Versus Conventional Radiation Therapy for the Palliation of Large Tumors

    University Health Network, Toronto · RECRUITING · PHASE3 · 2025-11-18

    Toronto, Ontario, Canada

  2. Treatment of Advanced Bulky Malignancies With Spatially Fractioned Radiation Therapy A Phase II Randomized Trial

    Summa Health System · TERMINATED · PHASE2 · 2003-02

    Akron, Ohio, United States

  3. A Prospective, Single-Arm Clinical Trial of Iparomlimab and Tuvonralimab Combined With Spatially Fractionated Radiotherapy and Definitive Chemoradiotherapy in Locoregionally Advanced Bulky Head and Neck Squamous Cell Carcinoma

    Second Affiliated Hospital of Nanchang University · NOT_YET_RECRUITING · PHASE2 · 2026-04-28

    Nanchang, Jiangxi, China

  4. A Pilot Study of Chemoimmunotherapy Combined With Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract Cancer

    University of Maryland, Baltimore · RECRUITING · PHASE1 · 2024-10-29

    Baltimore, Maryland, United States (+1 more site)

  5. Multicenter, Randomized Phase II Trial on Palliative Radiation With or Without Spatially Fractionated Radiotherapy Boost for Unresectable Bulky Malignancies

    Mayo Clinic · RECRUITING · NA · 2026-09-23

    Scottsdale, Arizona, United States (+1 more site)

  6. Phase II: Randomized Neoadjuvant Treatment of Oral Cavity Cancer With Spatially Fractionated Proton Radiotherapy and Immunotherapy (OSPRI)

    Mayo Clinic · NOT_YET_RECRUITING · PHASE2 · 2026-09-07

    Rochester, Minnesota, United States

  7. Evaluate the Efficacy and Safety of PD-L1 Monoclonal Antibody Combined With VEX Metronomic Chemotherapy With or Without Radiotherapy in Advanced Triple-negative Breast Cancer: a Prospective, Multicenter, Randomized Controlled Phase II Clinical Trial.

    Cancer Institute and Hospital, Chinese Academy of Medical Sciences · RECRUITING · PHASE2 · 2024-09-10

    Beijing, Beijing Municipality, China (+1 more site)

  8. An Umbrella Trial of Combining Different Radiotherapy Fractionation Patterns With Immunotherapy for Multiple Metastases of Non-Small Cell Lung Cancer

    Xinqiao Hospital of Chongqing · RECRUITING · PHASE2 · 2025-07-09

    Chongqing, Chongqing Municipality, China

  9. Spatially Fractionated Radiotherapy Combined With Chemo-immunotherapy for Locally Advanced Non-Small Cell Lung Cancer With Suboptimal Response to Initial Neoadjuvant Therapy: A Single-Arm, Open-Label, Phase II Study

    Tianjin Medical University Cancer Institute and Hospital · NOT_YET_RECRUITING · PHASE2 · 2026-07-01

    Tianjin, Tianjin Municipality, China

  10. A Randomized Controlled Clinical Trial of Spatially Fractionated Radiation Therapy for Locally Advanced Cervical Cancer

    The University of Hong Kong-Shenzhen Hospital · NOT_YET_RECRUITING · NA · 2026-09-01

    Shenzhen, Guangdong, China

  11. Spatially Fractionated Radiation (Grid) Therapy for Tumors of the Head & Neck, Thorax, Abdomen, Pelvis, and Extremities

    Mayo Clinic · COMPLETED · 2020-06-18

    Rochester, Minnesota, United States

  12. Spatially Fractionated Radiotherapy for Bulky or Refractory Solid Tumors: Efficacy and Toxicity

    The University of Hong Kong-Shenzhen Hospital · RECRUITING · PHASE1/PHASE2 · 2024-12-19

    Shenzhen, Guangdong, China

  13. A Phase 1 Study of Proton Pencil Beam Scanning GRID for Treatment of Bulky Tumors (ProGRID)

    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · ACTIVE_NOT_RECRUITING · NA · 2022-04-06

    Washington D.C., District of Columbia, United States

  14. A Phase II Prospective, Open-Label, Single-Arm Study Evaluating the Efficacy and Safety of Spatially Fractionated Radiotherapy Combined With Immunotherapy in Patients With Advanced Solid Tumors

    Tianjin Medical University Cancer Institute and Hospital · RECRUITING · PHASE2 · 2025-07-01

    Beijing, Beijing Municipality, China (+2 more sites)

  15. Effect of Neoadjuvant Radiation and Prediction of Response to Treatment in Locally Advanced Breast Cancer

    Fudan University · RECRUITING · PHASE2 · 2021-03-01

    Shanghai, Shanghai Municipality, China

  16. A Single-centre Phase II Clinical Study of Spatially Fragmentation Radiotherapy Combined With Low-dose Radiotherapy for Reversal of Immunotherapy Combined With Chemotherapy Resistance in Locally Advanced Inoperable or Advanced Non-small Cell Lung Cancer

    Tianjin Medical University Cancer Institute and Hospital · RECRUITING · PHASE2 · 2024-10-01

    Tianjin, Tianjin Municipality, China

  17. A Phase II Prospective Study of Preoperative Spatially Fractionated Radiation Therapy (SFRT) in Soft Tissue Sarcoma (neoSFRT-SARC)

    Second Affiliated Hospital, Zhejiang University, School of Medicine · RECRUITING · PHASE2 · 2026-03-16

    Hangzhou, Zhejiang, China

  18. A Prospective Study of Spatially Fractionated Radiation Treatment Using Rapid Rod Technique for Gynaecological Cancers

    Tata Memorial Hospital · RECRUITING · NA · 2024-10-04

    Navi Mumbai, Maharashtra, India

  19. Immune PET and Proteomics for the Assessment of Response to Spatially Fractionated or Palliative Radiotherapy With or Without Immunotherapy Ocena Efektu immunomodulującego Radioterapii Paliatywnej, w Tym Radioterapii z Przestrzennym zróżnicowaniem Dawki, Podanej Samodzielnie Lub z immunoterapią, u Chorych którzy Wyczerpali możliwość Leczenia Systemowego i Radioterapii Radykalnej, Przy Wykorzystaniu Immuno-PET i badań Proteomicznych

    Maria Sklodowska-Curie National Research Institute of Oncology · NOT_YET_RECRUITING · PHASE2 · 2025-06

  20. A Prospective Phase II Study of Radiation Therapy to Treat Refractory Breast Cancer

    Cancer Institute and Hospital, Chinese Academy of Medical Sciences · NOT_YET_RECRUITING · NA · 2026-06-30

    Beijing, Beijing Municipality, China