Clinical Trials

Actively registered and completed trials on Grid Therapy, Lattice Therapy, and SFRT, pulled directly from ClinicalTrials.gov.

Trials

Showing 20 of 41 trials
  1. A Phase I Trial of Palliative Spatially Fractionated (GRID) Radiotherapy Using Intensity Modulated Proton Therapy

    Washington University School of Medicine · ACTIVE_NOT_RECRUITING · NA · 2023-05-12

    St Louis, Missouri, United States

  2. A Phase II Prospective, Open-Label, Single-Arm Study Evaluating the Efficacy and Safety of Spatially Fractionated Radiotherapy Combined With Immunotherapy in Patients With Advanced Solid Tumors

    Tianjin Medical University Cancer Institute and Hospital · RECRUITING · PHASE2 · 2025-07-01

    Beijing, Beijing Municipality, China (+2 more sites)

  3. A Study of Spatially Fractionated Radiation Therapy Followed by Sequential Hypofractionated or Conventional Fractionated RT Combined With Iparomlimab and Tuvonralimab for Relapsed and Refractory Bulky Solid Tumors

    Second Affiliated Hospital of Nanchang University · RECRUITING · PHASE2 · 2025-06-20

    Nanchang, Jiangxi, China

  4. Spatially Fractionated Radiotherapy Combined With Chemo-immunotherapy for Locally Advanced Non-Small Cell Lung Cancer With Suboptimal Response to Initial Neoadjuvant Therapy: A Single-Arm, Open-Label, Phase II Study

    Tianjin Medical University Cancer Institute and Hospital · NOT_YET_RECRUITING · PHASE2 · 2026-07-01

    Tianjin, Tianjin Municipality, China

  5. Spatially Fractionated Radiotherapy Versus Conventional Radiotherapy in the Treatment of Soft Tissue Sarcoma:A Multicenter,Prospective, Phase II, Randomized Controlled Trial

    Shandong Cancer Hospital and Institute · RECRUITING · NA · 2025-05-20

    Jinan, Shandong, China

  6. A Pilot Study of Spatially Fractionated Radiation Therapy in Patients With Extra-Cranial Soft Tissue Metastases

    Memorial Sloan Kettering Cancer Center · RECRUITING · NA · 2023-07-24

    Basking Ridge, New Jersey, United States (+6 more sites)

  7. Phase II: Randomized Neoadjuvant Treatment of Oral Cavity Cancer With Spatially Fractionated Proton Radiotherapy and Immunotherapy (OSPRI)

    Mayo Clinic · NOT_YET_RECRUITING · PHASE2 · 2026-09-07

    Rochester, Minnesota, United States

  8. Spatially Fractionated Radiation (SFR) Therapy as Palliative Radiation for Patients With Advanced and Symptomatic Tumors

    Sir Mortimer B. Davis - Jewish General Hospital · RECRUITING · NA · 2015-01

    Montreal, Quebec, Canada

  9. A Prospective Phase II Study of Radiation Therapy to Treat Refractory Breast Cancer

    Cancer Institute and Hospital, Chinese Academy of Medical Sciences · NOT_YET_RECRUITING · NA · 2026-06-30

    Beijing, Beijing Municipality, China

  10. Spatially Fractionated Radiotherapy for Bulky or Refractory Solid Tumors: Efficacy and Toxicity

    The University of Hong Kong-Shenzhen Hospital · RECRUITING · PHASE1/PHASE2 · 2024-12-19

    Shenzhen, Guangdong, China

  11. Phase I Clinical Trial of GRID Therapy in Pediatric Osteosarcoma of the Extremity

    University of Arkansas · TERMINATED · NA · 2017-07-25

    Little Rock, Arkansas, United States

  12. First-in-Human Phase I and II Study to Determine Safety and Efficacy of Proton-Spatially Fractionated Radiotherapy (P-SFRT) in Retroperitoneal Soft Tissue Sarcoma

    Northwestern University · RECRUITING · PHASE1/PHASE2 · 2024-04-02

    Chicago, Illinois, United States

  13. A Phase II Randomized Controlled Clinical Study on the Efficacy and Safety Evaluation of Radiotherapy Mode Based on SFRT and SCART Technologies for Bone Metastatic Malignant Tumors With Soft Tissue Formation

    Shandong Cancer Hospital and Institute · RECRUITING · NA · 2025-06-01

    Jinan, Shandong, China

  14. A Prospective, Single-Arm Phase II Clinical Trial of Standard Systemic Therapy Combined With Spatial Fractionated Radiotherapy (SFRT) for Oligoprogressive Non-small Cell Lung Cancer (NSCLC)

    Second Affiliated Hospital, Zhejiang University, School of Medicine · RECRUITING · PHASE2 · 2025-06-15

    Hangzhou, Zhejiang, China

  15. An Umbrella Trial of Combining Different Radiotherapy Fractionation Patterns With Immunotherapy for Multiple Metastases of Non-Small Cell Lung Cancer

    Xinqiao Hospital of Chongqing · RECRUITING · PHASE2 · 2025-07-09

    Chongqing, Chongqing Municipality, China

  16. Grid Radiotherapy for Advanced Non-Small Cell Lung Cancer at the Time of Progression on Immune Checkpoint Inhibition

    Mayo Clinic · RECRUITING · PHASE2 · 2024-11-14

    Rochester, Minnesota, United States

  17. A Phase 1 Study of Proton Pencil Beam Scanning GRID for Treatment of Bulky Tumors (ProGRID)

    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · ACTIVE_NOT_RECRUITING · NA · 2022-04-06

    Washington D.C., District of Columbia, United States

  18. Spatially Fractionated Radiation (Grid) Therapy for Tumors of the Head & Neck, Thorax, Abdomen, Pelvis, and Extremities

    Mayo Clinic · COMPLETED · 2020-06-18

    Rochester, Minnesota, United States

  19. A Phase 2 Study of Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors

    University of Cincinnati · RECRUITING · PHASE2 · 2024-08-02

    Cincinnati, Ohio, United States

  20. A Single-centre Phase II Clinical Study of Spatially Fragmentation Radiotherapy Combined With Low-dose Radiotherapy for Reversal of Immunotherapy Combined With Chemotherapy Resistance in Locally Advanced Inoperable or Advanced Non-small Cell Lung Cancer

    Tianjin Medical University Cancer Institute and Hospital · RECRUITING · PHASE2 · 2024-10-01

    Tianjin, Tianjin Municipality, China